II C. Match the anti-histaminic drugs with respective pharmacokinetics. [4times 1=4Marks] Anti-histaminic agent 43. Desloratidine 44. Ebastine 45. Fexofenadine 46. Mizolastine Pharmacokinetics A. documented cardiac safety B. t_(1/2) of 8-10hr no active metabolites C. excreted unchanged in urine and bile D. yields active metabolite Carbastine

43. Desloratidine - B. of no active metabolites44. Ebastine - D. yields active metabolite Carbastine45. Fexofenadine - A. documented cardiac safety46. Mizolastine - C. excreted unchanged in urine and bile