Soru
NK - natural killer identifies the abnormalities on cells by detecting the amount of what? a. MHC I molecules b. Non-self -molecules C. PAMP - pathogen -associated molecular patterns d. PRR-pattern recognition receptors
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The correct answer is a. MHC I molecules.Natural killer (NK) cells are a type of immune cell that play a crucial role in the innate immune system. They are responsible for identifying and eliminating abnormal cells, such as tumor cells or virus-infected cells, in the body.NK cells identify abnormalities on cells by detecting the amount of major histocompatibility complex (MHC) class I molecules on the surface of the target cells. MHC class I molecules are proteins that are present on the surface of all nucleated cells in the body. They play a critical role in the immune system by presenting small fragments of proteins from inside the cell to the immune system. This allows the immune system to monitor the health of the cell and detect any abnormalities.Under normal circumstances, healthy cells express high levels of MHC class I molecules on their surface. However, when a cell becomes infected with a virus or becomes cancerous, the levels of MHC class I molecules on its surface can decrease. NK cells are able to detect these changes in MHC class I expression and target the abnormal cells for elimination.Therefore, the correct answer is a. MHC I molecules.