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IIB. Match theanti -histaminic drugs with respective additional mechanisms. [4times 1=4Marks] Anti-histaminic agent 39. Azelastine 40. Cetirizine 41. Promethazine 42. Rupatidine Additional mechanisms A. PAF antagonistic property B. high anti-cholinergic activity C. inhibits release of cytotoxic mediators D. downregulation of ICAM-1 expression

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IIB. Match theanti -histaminic drugs with respective additional mechanisms. [4times 1=4Marks]
Anti-histaminic agent
39. Azelastine
40. Cetirizine
41. Promethazine
42. Rupatidine
Additional mechanisms
A. PAF antagonistic property
B. high anti-cholinergic activity
C. inhibits release of cytotoxic mediators
D. downregulation of ICAM-1 expression

IIB. Match theanti -histaminic drugs with respective additional mechanisms. [4times 1=4Marks] Anti-histaminic agent 39. Azelastine 40. Cetirizine 41. Promethazine 42. Rupatidine Additional mechanisms A. PAF antagonistic property B. high anti-cholinergic activity C. inhibits release of cytotoxic mediators D. downregulation of ICAM-1 expression

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39. Azelastine - C. inhibits release of cytotoxic mediators<br />40. Cetirizine - A. PAF antagonistic property<br />41. Promethazine - B. high anti-cholinergic activity<br />42. Rupatidine - D. downregulation of ICAM-1 expression
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