An antibody-based drug is one candidate for a more effective , longer lasting overdose treatment. To explore this possibility, a team at Scripps Research Institute led by Kim D. Janda first treated mice with a vaccine that stimulated the animals to produce a slew of different antibodies against fentanyl, some of which helped protect the mice from overdoses. In the new work the team recovered antibodies from the mice, purified them, and screened them for their ability to bind fentanyl. The team evaluated six of these antibodies against nine fentanyl analogs commonly confiscated by law enforcement. One antibody.6A4, demonstrated the best fentanyl- binding affinity and had a six- day half-life in mice. Which choice best explains why the author most likely included the information that the drugs were "commonly confiscated by law enforcement"? A) To explain how the researchers obtained drugs for experimentation B) To indicate that the research would apply to overdoses in authentic cases C) To eliminate the argument that the trials were improperly conducted D) To establish why special permits were needed to experiment with the drugs

## Step 1<br />The problem is a comprehension question that requires understanding the context and the purpose of the information provided in the text. The text discusses a research study where mice were vaccinated to produce antibodies against fentanyl, a potent opioid. The researchers then tested these antibodies against nine fentanyl analogs that are commonly confiscated by law enforcement.<br /><br />## Step 2<br />The question asks us to determine why the author included the information that the drugs were "commonly confiscated by law enforcement". The options provided suggest different reasons, but we need to choose the one that best fits the context of the text.<br /><br />## Step 3<br />Option A suggests that the information was included to explain how the researchers obtained the drugs. However, the text does not provide any information about how the drugs were obtained.<br /><br />## Step 4<br />Option B suggests that the information was included to indicate that the research would apply to overdoses in authentic cases. This seems to be a plausible reason as the drugs being tested are those that are commonly found in real-life overdose cases.<br /><br />## Step 5<br />Option C suggests that the information was included to eliminate the argument that the trials were improperly conducted. However, the text does not provide any information about the conduct of the trials.<br /><br />## Step 6<br />Option D suggests that the information was included to establish why special permits were needed to experiment with the drugs. However, the text does not provide any information about the need for special permits.